Cranberry extract initiates intrinsic apoptosis in HL-60 cells by increasing BAD activity through inhibition of AKT phosphorylation

Cranberry extract initiates intrinsic apoptosis in HL-60 cells by increasing BAD activity through inhibition of AKT phosphorylation

Abstract Background Cranberry has been studied as a potential anticancer agent as it is capable of inducing apoptosis within cancer cells. The aim of this study was to better define the mechanism by which cranberry triggers apoptosis in HL-60 cells. Methods The study was carried on cranberry extract...

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Bibliographic Details
Main Authors: Rasha A. Mansouri, Susan S. Percival
Format: Article
Language:English
Published: BMC 2020-03-01
Series:BMC Complementary Medicine and Therapies
Subjects:
Cranberry
HL-60
Apoptosis
Caspases
Protein kinase B (Akt)
BCL-2-associated death promoter (BAD)
Online Access:http://link.springer.com/article/10.1186/s12906-020-2870-4

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http://link.springer.com/article/10.1186/s12906-020-2870-4

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