TIPE1 Promotes Cervical Cancer Cell Chemoresistance to Cisplatin in a Wild-Type p53-Dependent Manner

Previous studies have revealed that TIPE1 serves as a tumor suppressor gene in several tumor types. However, we demonstrated that TIPE1 can promote cervical cancer proliferation by suppressing p53 activity. Here, we showed that TIPE1 inhibits cervical cancer cell apoptosis both in vivo and in vitro....

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Bibliographic Details
Main Authors: Jie Jiang, Li Gao, Yongting Lan, Yang Wang, Peiqing Zhao
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-01-01
Series:Frontiers in Oncology
Subjects:
p53
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2020.593615/full