Persistent humoral immune responses in the CNS limit recovery of reactivated murine cytomegalovirus.

Experimental infection of the mouse brain with murine CMV (MCMV) elicits neuroimmune responses that terminate acute infection while simultaneously preventing extensive bystander damage. Previous studies have determined that CD8(+) T lymphocytes are required to restrict acute, productive MCMV infecti...

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Bibliographic Details
Main Authors: Manohar B Mutnal, Shuxian Hu, James R Lokensgard
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3295797?pdf=render