Glucosylceramide metabolism is regulated during normal and hormonally stimulated epidermal barrier development in the rat

Glucosylceramides, delivered to the stratum corneum interstices by exocytosis of lamellar body contents, are enzymatically hydrolyzed to ceramides, which are major components of the lipid lamellar bilayers that mediate epidermal barrier function. Because this conversion is critical for permeability...

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Bibliographic Details
Main Authors: K Hanley, Y Jiang, W M Holleran, P M Elias, M L Williams, K R Feingold
Format: Article
Language:English
Published: Elsevier 1997-03-01
Series:Journal of Lipid Research
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520372655