Computational modeling and numerical methods for spatiotemporal calcium cycling in ventricular myocytes

Computational modeling and numerical methods for spatiotemporal calcium cycling in ventricular myocytes

Intracellular calcium (Ca) cycling dynamics in cardiac myocytes is regulated by a complex network of spatially distributed organelles, such as sarcoplasmic reticulum (SR), mitochondria, and myofibrils. In this study, we present a mathematical model of intracellular Ca cycling and numerical and compu...

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Bibliographic Details
Main Authors: Michael eNivala, Enno ede Lange, Robert eRovetti, Zhilin eQu
Format: Article
Language:English
Published: Frontiers Media S.A. 2012-05-01
Series:Frontiers in Physiology
Subjects:
mathematical modeling
calcium cycling
graphical processing unit computing
ventricular myocyte
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphys.2012.00114/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fphys.2012.00114/full

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