Neonatal brain injury causes cerebellar learning deficits and Purkinje cell dysfunction

Premature infants are vulnerable to hypoxia and thus white matter injury, especially in the cerebellum, which develops during late gestation. Here, the authors test the effects of perinatal hypoxia on motor performance and rescue behavioral deficits using the GABA reuptake inhibitor Tiagabine.

Bibliographic Details
Main Authors: Aaron Sathyanesan, Srikanya Kundu, Joseph Abbah, Vittorio Gallo
Format: Article
Language:English
Published: Nature Publishing Group 2018-08-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-018-05656-w