Nanoparticle inhalation augments particle-dependent systemic microvascular dysfunction

<p>Abstract</p> <p>Background</p> <p>We have shown that pulmonary exposure to fine particulate matter (PM) impairs endothelium dependent dilation in systemic arterioles. Ultrafine PM has been suggested to be inherently more toxic by virtue of its increased surface area....

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Bibliographic Details
Main Authors: Cumpston Jared L, Hubbs Ann F, Porter Dale W, Nurkiewicz Timothy R, Chen Bean T, Frazer David G, Castranova Vincent
Format: Article
Language:English
Published: BMC 2008-02-01
Series:Particle and Fibre Toxicology
Online Access:http://www.particleandfibretoxicology.com/content/5/1/1