Protopine triggers apoptosis via the intrinsic pathway and regulation of ROS/PI3K/Akt signalling pathway in liver carcinoma

Abstract Background Protopine is an isoquinoline alkaloid that possesses various biological activities including the anti-tumour activity. However, the effects of protopine on liver carcinoma cells are still elusive. The aim of this study is to examine the effects of protopine on liver carcinoma cel...

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Bibliographic Details
Main Authors: Chunhui Nie, Bei Wang, Baoquan Wang, Ning Lv, Rui Yu, Enfan Zhang
Format: Article
Language:English
Published: BMC 2021-07-01
Series:Cancer Cell International
Subjects:
ROS
Online Access:https://doi.org/10.1186/s12935-021-02105-5