Influence of Statins on Survival Outcome in Patients with Metastatic Castration Resistant Prostate Cancer Treated with Abiraterone Acetate.

Even though the exact mechanism is largely unknown until now, statins are supposed to improve survival outcomes in various malignancies. For prostate cancer however, statins are known to compete with dehydroepiandrosterone (DHEAS) for the transport into the cytosol both using the cell by the Solute...

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Bibliographic Details
Main Authors: Martin Boegemann, Katrin Schlack, Ann-Kathrin Fischer, Joachim Gerß, Julie Steinestel, Axel Semjonow, Andres Jan Schrader, Laura-Maria Krabbe
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5008748?pdf=render