Comparison of Direct Oral Anticoagulant Use for the Treatment of Non-Valvular Atrial Fibrillation in Pivotal Clinical Trials vs. the Real-World Setting: A Population-Based Study from Southern Italy

Patients enrolled into pivotal randomized controlled trials (RCTs) may differ substantially from those treated in a real-world (RW) setting, which may result in a different benefit–risk profile. The aim of the study was to assess the external validity of pivotal RCT findings concerning direct oral a...

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Bibliographic Details
Main Authors: Ylenia Ingrasciotta, Andrea Fontana, Anna Mancuso, Valentina Ientile, Janet Sultana, Ilaria Uomo, Maurizio Pastorello, Paolo Calabrò, Giuseppe Andò, Gianluca Trifirò
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:Pharmaceuticals
Subjects:
Online Access:https://www.mdpi.com/1424-8247/14/4/290