Carbonate Apatite Nanoparticles-Facilitated Intracellular Delivery of siRNA(s) Targeting Calcium Ion Channels Efficiently Kills Breast Cancer Cells

Carbonate Apatite Nanoparticles-Facilitated Intracellular Delivery of siRNA(s) Targeting Calcium Ion Channels Efficiently Kills Breast Cancer Cells

Specific gene knockdown facilitated by short interfering RNA (siRNA) is a potential approach for suppressing the expression of ion channels and transporter proteins to kill breast cancer cells. The overexpression of calcium ion channels and transporter genes is seen in the MCF-7 breast cancer cell l...

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Bibliographic Details
Main Authors: Mohammad Borhan Uddin, Balakavitha Balaravi Pillai, Kyi Kyi Tha, Maeirah Ashaie, Md. Emranul Karim, Ezharul Hoque Chowdhury
Format: Article
Language:English
Published: MDPI AG 2018-06-01
Series:Toxics
Subjects:
carbonate apatite
siRNA
MCF-7 breast cancer cell
cytotoxicity
ion channels and transporter genes
Online Access:http://www.mdpi.com/2305-6304/6/3/34

Internet

http://www.mdpi.com/2305-6304/6/3/34

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