The role of potassium channel activation in celecoxib-induced analgesic action.

BACKGROUND AND PURPOSE: Celecoxib (CXB) is a widely prescribed COX-2 inhibitor used clinically to treat pain and inflammation. Recently, COX-2 independent mechanisms have been described to be the targets of CXB. For instance, ion channels such as the voltage-gated sodium channel, L-type calcium chan...

Full description

Bibliographic Details
Main Authors: Yao Mi, Xuan Zhang, Fan Zhang, Jinlong Qi, Haixia Gao, Dongyang Huang, Li Li, Hailin Zhang, Xiaona Du
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3554616?pdf=render