Hexagonal Mesoporous Silica as a Rapid, Efficient and Versatile Tool for MALDI-TOF MS Sample Preparation in Clinical Peptidomics Analysis: A Pilot Study

Hexagonal Mesoporous Silica as a Rapid, Efficient and Versatile Tool for MALDI-TOF MS Sample Preparation in Clinical Peptidomics Analysis: A Pilot Study

Improvement in high-throughput MALDI-TOF MS analysis requires practical and efficient sample preparation protocols for high acquisition rates. The use of hexagonal mesoporous silica (HMS) sorbents in combination with MALDI-TOF MS was explored as a versatile tool for peptidomic profiling of clinical...

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Bibliographic Details
Main Authors: Rosa Terracciano, Mariaimmacolata Preianò, Giuseppina Maggisano, Corrado Pelaia, Rocco Savino
Format: Article
Language:English
Published: MDPI AG 2019-06-01
Series:Molecules
Subjects:
MALDI-TOF
peptidomics
profiling
fingerprinting
biomarkers
sample preparation
analytical chemistry
Online Access:https://www.mdpi.com/1420-3049/24/12/2311

Internet

https://www.mdpi.com/1420-3049/24/12/2311

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