A robust intracellular metabolite extraction protocol for human neutrophil metabolic profiling.

Neutrophils are phagocytic innate immune cells that play essential roles in host defence, but are also implicated in inflammatory diseases such as rheumatoid arthritis (RA) where they contribute to systemic inflammation and joint damage. Transcriptomic analysis of neutrophils has revealed significan...

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Bibliographic Details
Main Authors: Susama Chokesuwattanaskul, Marie M Phelan, Steven W Edwards, Helen L Wright
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0209270