Mechanistic insights into the intracellular release of doxorubicin from pH-sensitive liposomes

Mechanistic insights into the intracellular release of doxorubicin from pH-sensitive liposomes

pH-sensitive liposomes are interesting carriers for drug-delivery, undertaking rapid bilayer destabilization in response to pH changes, allied to tumor accumulation, a desirable behavior in the treatment of cancer cells. Previously, we have shown that pH-sensitive liposomes accumulate in tumor tissu...

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Bibliographic Details
Main Authors: Samara Bonesso dos Reis, Juliana de Oliveira Silva, Fernanda Garcia-Fossa, Elaine Amaral Leite, Angelo Malachias, Gwenaelle Pound-Lana, Vanessa Carla Furtado Mosqueira, Mônica Cristina Oliveira, André Luís Branco de Barros, Marcelo Bispo de Jesus
Format: Article
Language:English
Published: Elsevier 2021-02-01
Series:Biomedicine & Pharmacotherapy
Subjects:
pH-sensitive liposomes
Doxorubicin
Drug delivery system
Intracellular release
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332220311446

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http://www.sciencedirect.com/science/article/pii/S0753332220311446

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