Antiallodynic and anti-inflammatory effects of intrathecal R-PIA in a rat model of vincristine-induced peripheral neuropathy

Background Studies investigating the correlation between spinal adenosine A1 receptors and vincristine-induced peripheral neuropathy (VIPN) are limited. This study explored the role of intrathecal N6-(2-phenylisopropyl)-adenosine R-(-)isomer (R-PIA) in the rat model of VIPN. Methods Vincristine (100...

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Bibliographic Details
Main Authors: Kyungmi Kim, Wonyeong Jeong, In Gu Jun, Jong Yeon Park
Format: Article
Language:English
Published: Korean Society of Anesthesiologists 2020-10-01
Series:Korean Journal of Anesthesiology
Subjects:
Online Access:http://ekja.org/upload/pdf/kja-19481.pdf