A novel and well-defined benchmarking method for second generation read mapping

<p>Abstract</p> <p>Background</p> <p>Second generation sequencing technologies yield DNA sequence data at ultra high-throughput. Common to most biological applications is a mapping of the reads to an almost identical or highly similar reference genome. The assessment of...

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Bibliographic Details
Main Authors: Weese David, Emde Anne-Katrin, Holtgrewe Manuel, Reinert Knut
Format: Article
Language:English
Published: BMC 2011-05-01
Series:BMC Bioinformatics
Online Access:http://www.biomedcentral.com/1471-2105/12/210