C-Reactive Protein Promotes the Expansion of Myeloid Derived Cells With Suppressor Functions

C-Reactive Protein Promotes the Expansion of Myeloid Derived Cells With Suppressor Functions

Previously we established that human C-reactive protein (CRP) exacerbates mouse acute kidney injury and that the effect was associated with heightened renal accumulation of myeloid derived cells with suppressor functions (MDSC). Herein we provide direct evidence that CRP modulates the development an...

Full description

Bibliographic Details
Main Authors: Rachel V. Jimenez, Valeriya Kuznetsova, Ashley N. Connelly, Zdenek Hel, Alexander J. Szalai
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-09-01
Series:Frontiers in Immunology
Subjects:
acute phase response
inflammation
myelopoiesis
innate immunity
cancer
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.02183/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2019.02183/full

Similar Items