Rupintrivir reduces RV-induced TH-2 cytokine IL-4 in precision-cut lung slices (PCLS) of HDM-sensitized mice ex vivo

Rupintrivir reduces RV-induced TH-2 cytokine IL-4 in precision-cut lung slices (PCLS) of HDM-sensitized mice ex vivo

Abstract Background Antiviral drugs such as rupintrivir may have an immune-modulatory effect in experimentally induced allergic asthma with subsequent RV infection. We infected lung slices of house-dust mite (HDM)-sensitized asthmatic mice ex vivo with human rhinovirus (RV) and investigated the effe...

Full description

Bibliographic Details
Main Authors: Olga Danov, Lisa Lasswitz, Helena Obernolte, Christina Hesse, Armin Braun, Sabine Wronski, Katherina Sewald
Format: Article
Language:English
Published: BMC 2019-10-01
Series:Respiratory Research
Subjects:
Rhinovirus
Infection
Asthma
Exacerbation
Lung sections
Online Access:http://link.springer.com/article/10.1186/s12931-019-1175-y

Internet

http://link.springer.com/article/10.1186/s12931-019-1175-y

Similar Items