Structural variation in mouse genomes

Structural variation in mouse genomes

Traditionally, the identification of structural variation in genomes has been challenging. However, with the recent advances in high-throughput DNA sequencing and paired-end mapping (PEM) methods, the ability to identify structural variation and their respective association to human diseases has imp...

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Bibliographic Details
Main Authors: Thomas M Keane, Kim eWong, David J Adams, Jonathan eFlint, Alexandre eReymond, Binnaz eYalcin
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-07-01
Series:Frontiers in Genetics
Subjects:
inbred strains of mice
Array comparative genome hybridization (aCGH)
next-generation sequencing (NGS)
structural variation (SV)
paired-end mapping (PEM)
Heteregeneous Stock (HS)
Online Access:http://journal.frontiersin.org/Journal/10.3389/fgene.2014.00192/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fgene.2014.00192/full

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