CdiA Effectors Use Modular Receptor-Binding Domains To Recognize Target Bacteria

Contact-dependent growth inhibition (CDI) systems encode CdiA effectors, which bind to specific receptors on neighboring bacteria and deliver C-terminal toxin domains to suppress target cell growth. Two classes of CdiA effectors that bind distinct cell surface receptors have been identified, but the...

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Bibliographic Details
Main Authors: Zachary C. Ruhe, Josephine Y. Nguyen, Jing Xiong, Sanna Koskiniemi, Christina M. Beck, Basil R. Perkins, David A. Low, Christopher S. Hayes, Michael T. Laub
Format: Article
Language:English
Published: American Society for Microbiology 2017-03-01
Series:mBio
Online Access:http://mbio.asm.org/cgi/content/full/8/2/e00290-17