High affinity antibodies to Plasmodium falciparum merozoite antigens are associated with protection from malaria.

BACKGROUND: Malaria kills almost 1 million people every year, but the mechanisms behind protective immunity against the disease are still largely unknown. METHODOLOGY/PRINCIPAL FINDINGS: In this study, surface plasmon resonance technology was used to evaluate the affinity (measured as k(d)) of natur...

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Bibliographic Details
Main Authors: Sreenivasulu B Reddy, Robin F Anders, James G Beeson, Anna Färnert, Fred Kironde, Sharon Kühlman Berenzon, Mats Wahlgren, Sara Linse, Kristina E M Persson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3283742?pdf=render