Gender-specific metabolomic profiling of obesity in leptin-deficient ob/ob mice by 1H NMR spectroscopy.

Despite the numerous metabolic studies on obesity, gender bias in obesity has rarely been investigated. Here, we report the metabolomic analysis of obesity by using leptin-deficient ob/ob mice based on the gender. Metabolomic analyses of urine and serum from ob/ob mice compared with those from C57BL...

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Main Authors: Eun-Young Won, Mi-Kyung Yoon, Sang-Woo Kim, Youngae Jung, Hyun-Whee Bae, Daeyoup Lee, Sung Goo Park, Chul-Ho Lee, Geum-Sook Hwang, Seung-Wook Chi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3789719?pdf=render