From Binary to Multivalued to Continuous Models: The lac Operon as a Case Study
Using the lac operon as a paradigmatic example for a gene regulatory system in prokaryotes, we demonstrate how qualitative knowledge can be initially captured using simple discrete (Boolean) models and then stepwise refined to multivalued logical models and finally to continuous (ODE) models. At all...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
De Gruyter
2010-03-01
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| Series: | Journal of Integrative Bioinformatics |
| Online Access: | http://www.degruyter.com/view/j/jib.2010.7.issue-1/biecoll-jib-2010-151/biecoll-jib-2010-151.xml?format=INT |