Synthesis, X-ray Single Crystal, Conformational Analysis and Cholinesterase Inhibitory Activity of a New Spiropyrrolidine Scaffold Tethered Benzo[<i>b</i>]Thiophene Analogue

Synthesis, X-ray Single Crystal, Conformational Analysis and Cholinesterase Inhibitory Activity of a New Spiropyrrolidine Scaffold Tethered Benzo[<i>b</i>]Thiophene Analogue

Described herein is a one-pot protocol for the synthesis of a substituted spiropyrrolidine scaffold tethered benzo[<i>b</i>]thiophene analogue from (<i>E</i>)-3-(benzo[<i>b</i>]thiophen-2-yl)-1-(4-fluoro- phenyl)-prop-2-en-1-one. The described protocol has the adv...

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Bibliographic Details
Main Authors: Assem Barakat, Saied M. Soliman, Saeed Alshahrani, Mohammad Shahidul Islam, M. Ali, Abdullah Mohammed Al-Majid, Sammer Yousuf
Format: Article
Language:English
Published: MDPI AG 2020-02-01
Series:Crystals
Subjects:
spiropyrrolidine
thiazole
benzo[<i>b</i>]thiophene
conformational analysis
cholinesterase inhibitory activity
Online Access:https://www.mdpi.com/2073-4352/10/2/120

Internet

https://www.mdpi.com/2073-4352/10/2/120

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