Novel TRPV1 Channel Agonists With Faster and More Potent Analgesic Properties Than Capsaicin

Novel TRPV1 Channel Agonists With Faster and More Potent Analgesic Properties Than Capsaicin

The transient receptor potential vanilloid 1 (TRPV1) ion channel is a member of the family of Transient Receptor Potential (TRP) channels that acts as a molecular detector of noxious signals in primary sensory neurons. Activated by capsaicin, heat, voltage and protons, it is also well known for its...

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Bibliographic Details
Main Authors: Yorley Duarte, Javier Cáceres, Romina V. Sepúlveda, Diego Arriagada, Pedro Olivares, Ignacio Díaz-Franulic, Jimmy Stehberg, Fernando González-Nilo
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-07-01
Series:Frontiers in Pharmacology
Subjects:
transient receptor potential vanilloid 1 channels
TRPV1
drug discovery
capsaicin
analgesic
carrageenan
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2020.01040/full

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https://www.frontiersin.org/article/10.3389/fphar.2020.01040/full

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