Subdominant antigens in bacterial vaccines: AM779 is subdominant in the Anaplasma marginale outer membrane vaccine but does not associate with protective immunity.

Subdominant antigens in bacterial vaccines: AM779 is subdominant in the Anaplasma marginale outer membrane vaccine but does not associate with protective immunity.

Identification of specific antigens responsible for the ability of complex immunogens to induce protection is a major goal in development of bacterial vaccines. Much of the investigation has focused on highly abundant and highly immunodominant outer membrane proteins. Recently however, genomic and p...

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Bibliographic Details
Main Authors: Saleh M Albarrak, Wendy C Brown, Susan M Noh, Kathryn E Reif, Glen A Scoles, Joshua E Turse, Junzo Norimine, Massaro W Ueti, Guy H Palmer
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3460813?pdf=render

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http://europepmc.org/articles/PMC3460813?pdf=render

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