Left ventricular ejection fraction decrease related to BRAF and/or MEK inhibitors in metastatic melanoma patients: A retrospective analysis

Left ventricular ejection fraction decrease related to BRAF and/or MEK inhibitors in metastatic melanoma patients: A retrospective analysis

Abstract BRAF and MEKis have revolutionized the management of BRAFV600‐mutated melanoma patients. Left ventricular ejection fraction decrease (LVEF‐D) related to these treatments has not been thoroughly evaluated to date. The main objective of this study was to describe characteristics of LVEF‐D in...

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Bibliographic Details
Main Authors: Mathilde Berger, Mona Amini‐Adlé, Delphine Maucort‐Boulch, Philip Robinson, Luc Thomas, Stéphane Dalle, Pierre‐Yves Courand
Format: Article
Language:English
Published: Wiley 2020-04-01
Series:Cancer Medicine
Subjects:
adverse events
BRAF inhibitor
cardiac toxicity
heart failure
left ventricular ejection fraction
left ventricular systolic dysfunction
Online Access:https://doi.org/10.1002/cam4.2922

Internet

https://doi.org/10.1002/cam4.2922

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