Identification of mosquito sterol carrier protein-2 inhibitors

A mosquito sterol carrier protein-2, AeSCP-2, has been shown to aid in the uptake of cholesterol in mosquito cells. The discovery of chemical inhibitors of AeSCP-2 is reported here. AeSCP-2 inhibitors (SCPIs) belong to several chemotypes of hydrophobic compounds. Those inhibitors competed with chole...

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Bibliographic Details
Main Authors: Min-sik Kim, Vilena Wessely, Que Lan
Format: Article
Language:English
Published: Elsevier 2005-04-01
Series:Journal of Lipid Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520339997