Anthracyclines, proteasome activity and multi-drug-resistance

<p>Abstract</p> <p>Background</p> <p>P-glycoprotein is responsible for the ATP-dependent export of certain structurally unrelated compounds including many chemotherapeutic drugs. Amplification of P-glycoprotein activity can result in multi-drug resistance and is a commo...

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Bibliographic Details
Main Authors: Pajonk Frank, McBride William H, Fekete Mirela R
Format: Article
Language:English
Published: BMC 2005-09-01
Series:BMC Cancer
Online Access:http://www.biomedcentral.com/1471-2407/5/114