A Dengue Virus Type 4 Model of Disseminated Lethal Infection in AG129 Mice.

Dengue is a mosquito-borne disease of global public health significance that is caused by four serologically and genetically related viruses (DENV-1 to DENV-4). Most human DENV infections are asymptomatic, but clinical cases can range in severity from a relatively mild self-limiting illness to a sev...

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Bibliographic Details
Main Authors: Gregg N Milligan, Vanessa V Sarathy, Ernesto Infante, Li Li, Gerald A Campbell, P Robert Beatty, Eva Harris, Alan D T Barrett, Nigel Bourne
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4418603?pdf=render