Hypoxia Modulates Effects of Fatty Acids on NES2Y Human Pancreatic β-cells

Saturated fatty acids (FAs) induce apoptosis in the human pancreatic NES2Y β-cell line while unsaturated FAs have nearly no detrimental effect. Moreover, unsaturated FAs are capable of inhibiting the pro-apoptotic effect of saturated FAs. Hypoxia is also known to have deleterious effects on...

Full description

Bibliographic Details
Main Authors: Jan Šrámek, Vlasta Němcová-Fürstová, Jan Polák, Jan Kovář
Format: Article
Language:English
Published: MDPI AG 2019-07-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:https://www.mdpi.com/1422-0067/20/14/3441