Effects of Transforming Growth Factor Beta 1 in Cerebellar Development: Role in Synapse Formation

Effects of Transforming Growth Factor Beta 1 in Cerebellar Development: Role in Synapse Formation

Granule cells (GC) are the most numerous glutamatergic neurons in the cerebellar cortex and represent almost half of the neurons of the Central Nervous System (CNS). Despite recent advances, the mechanisms of how the glutamatergic synapses are formed in the cerebellum remain unclear. Among the TGF-β...

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Bibliographic Details
Main Authors: Ana Paula Bergamo Araujo, Luan Pereira Diniz, Cristiane Monteiro Eller, Beatriz Gomes de Matos, Rodrigo eMartinez, Flavia Carvalho Alcantara Gomes
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-04-01
Series:Frontiers in Cellular Neuroscience
Subjects:
Cerebellum
development
Migration
Excitatory synapses
TGF-β1
Online Access:http://journal.frontiersin.org/Journal/10.3389/fncel.2016.00104/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fncel.2016.00104/full

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