Analysis in conditional cannabinoid 1 receptor-knockout mice reveals neuronal subpopulation-specific effects on epileptogenesis in the kindling paradigm

The endocannabinoid system serves as a retrograde negative feedback mechanism. It is thought to control neuronal activity in an epileptic neuronal network. The purpose of this study was to evaluate the impact of the endocannabinoid and endovanilloid systems on both epileptogenesis and ictogenesis.Th...

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Bibliographic Details
Main Authors: E.L. von Rüden, M. Jafari, R.M. Bogdanovic, C.T. Wotjak, H. Potschka
Format: Article
Language:English
Published: Elsevier 2015-01-01
Series:Neurobiology of Disease
Subjects:
CB1
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996114002307