Induction of cytotoxic T lymphocytes primed with Tumor RNA-loaded Dendritic Cells in esophageal squamous cell carcinoma: preliminary step for DC vaccine design

<p>Abstract</p> <p>Background</p> <p>Dendritic Cells (DC) are potent antigen presenting cells with the ability to prime naïve T cells and convert them to cytotoxic T-lymphocytes (CTL). We evaluated the capability of autologous DCs transfected with total tumor and normal...

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Main Authors: Malekzadeh Reza, Forghani Mohammad, Memar Bahram, Sankian Mojtaba, Mahmoudi Mahmoud, Farshchian Moein, Moaven Omeed, Gholamin Mehran, Rajabi-Mashhadi Mohammad, Abbaszadegan Mohammad
Format: Article
Language:English
Published: BMC 2010-06-01
Series:BMC Cancer
Online Access:http://www.biomedcentral.com/1471-2407/10/261