AhR Ligands Modulate the Differentiation of Innate Lymphoid Cells and T Helper Cell Subsets That Control the Severity of a Pulmonary Fungal Infection

AhR Ligands Modulate the Differentiation of Innate Lymphoid Cells and T Helper Cell Subsets That Control the Severity of a Pulmonary Fungal Infection

In agreement with other fungal infections, immunoprotection in pulmonary paracoccidioidomycosis (PCM) is mediated by Th1/Th17 cells whereas disease progression by prevalent Th2/Th9 immunity. Treg cells play a dual role, suppressing immunity but also controlling excessive tissue inflammation. Our rec...

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Bibliographic Details
Main Authors: Eliseu F. de Araújo, Flávio V. Loures, Nycolas W. Preite, Cláudia Feriotti, Nayane AL Galdino, Tânia A. Costa, Vera L. G. Calich
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-04-01
Series:Frontiers in Immunology
Subjects:
innate lymphoid cells (ILCs)
L-kynurenine
FICZ
T cell subsets
paracoccidiodomycosis
IDO - Indoleamine 2 3-dioxygenase
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.630938/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2021.630938/full

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