Frequency and origin of haplotypes associated with the beta-globin gene cluster in individuals with trait and sickle cell anemia in the Atlantic and Pacific coastal regions of Colombia

Sickle cell anemia is a genetic disease with high prevalence in people of African descent. There are five typical haplotypes associated with this disease and the haplotypes associated with the beta-globin gene cluster have been used to establish the origin of African-descendant people in America. In...

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Bibliographic Details
Main Authors: Cristian Fong, María Alejandra Lizarralde-Iragorri, Diana Rojas-Gallardo, Guillermo Barreto
Format: Article
Language:English
Published: Sociedade Brasileira de Genética 2013-01-01
Series:Genetics and Molecular Biology
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572013000400005&lng=en&tlng=en