Integrated Genome-Wide Analysis of an Isogenic Pair of <i>Pseudomonas aeruginosa</i> Clinical Isolates with Differential Antimicrobial Resistance to Ceftolozane/Tazobactam, Ceftazidime/Avibactam, and Piperacillin/Tazobactam

Integrated Genome-Wide Analysis of an Isogenic Pair of <i>Pseudomonas aeruginosa</i> Clinical Isolates with Differential Antimicrobial Resistance to Ceftolozane/Tazobactam, Ceftazidime/Avibactam, and Piperacillin/Tazobactam

Multidrug-resistant (MDR) <i>Pseudomonas aeruginosa</i> is one of the main causes of morbidity and mortality in hospitalized patients and the leading cause of nosocomial infections. We investigated, here, two MDR <i>P. aeruginosa</i> clinical isolates from a hospitalized pati...

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Bibliographic Details
Main Authors: Weihua Huang, Joelle El Hamouche, Guiqing Wang, Melissa Smith, Changhong Yin, Abhay Dhand, Nevenka Dimitrova, John T. Fallon
Format: Article
Language:English
Published: MDPI AG 2020-02-01
Series:International Journal of Molecular Sciences
Subjects:
<i>pseudomonas aeruginosa</i>
whole-genome sequencing (wgs)
epigenetic profiling
rna sequencing (rnaseq)
antimicrobial resistance
ceftolozane/tazobactam (c/t)
ceftazidime/avibactam (cza)
piperacillin/tazobactam (p/t)
Online Access:https://www.mdpi.com/1422-0067/21/3/1026

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https://www.mdpi.com/1422-0067/21/3/1026

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