A Manganese Superoxide Dismutase (SOD2) Gene Polymorphism in Insulin-Dependent Diabetes Mellitus

Interleukin I (lL-I) is selectively cytotoxic to the insulin producing beta cell of pancreatic islets. This effect may be due to IL-I induced generation of reactive oxygen species and nitric oxide. Since beta cells contain low amounts of the superoxide radical scavenger enzyme manganese superoxide d...

Full description

Bibliographic Details
Main Authors: Flemming Pociot, Tove Lorenzen, JøRn Nerup
Format: Article
Language:English
Published: Hindawi Limited 1993-01-01
Series:Disease Markers
Online Access:http://dx.doi.org/10.1155/1993/678310