A Manganese Superoxide Dismutase (SOD2) Gene Polymorphism in Insulin-Dependent Diabetes Mellitus
Interleukin I (lL-I) is selectively cytotoxic to the insulin producing beta cell of pancreatic islets. This effect may be due to IL-I induced generation of reactive oxygen species and nitric oxide. Since beta cells contain low amounts of the superoxide radical scavenger enzyme manganese superoxide d...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Hindawi Limited
1993-01-01
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Series: | Disease Markers |
Online Access: | http://dx.doi.org/10.1155/1993/678310 |