Actin activates Pseudomonas aeruginosa ExoY nucleotidyl cyclase toxin and ExoY-like effector domains from MARTX toxins

Actin activates Pseudomonas aeruginosa ExoY nucleotidyl cyclase toxin and ExoY-like effector domains from MARTX toxins

The ExoY toxin is injected by Pseudomonas aeruginosainto host cells, where it is activated by an unknown host factor. Here the authors identify such factor as filamentous actin.

Bibliographic Details
Main Authors: Alexander Belyy, Dorothée Raoux-Barbot, Cosmin Saveanu, Abdelkader Namane, Vasily Ogryzko, Lina Worpenberg, Violaine David, Veronique Henriot, Souad Fellous, Christien Merrifield, Elodie Assayag, Daniel Ladant, Louis Renault, Undine Mechold
Format: Article
Language:English
Published: Nature Publishing Group 2016-12-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/ncomms13582

Internet

https://doi.org/10.1038/ncomms13582

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