Molecular characterization of acquired tolerance of tumor cells to picropodophyllin (PPP).

Molecular characterization of acquired tolerance of tumor cells to picropodophyllin (PPP).

BACKGROUND: Picropodophyllin (PPP) is a promising novel anti-neoplastic agent that efficiently kills tumor cells in vitro and causes tumor regression and increased survival in vivo. We have previously reported that PPP treatment induced moderate tolerance in two out of 10 cell lines only, and here r...

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Main Authors: Jamileh Hashemi, Claire Worrall, Daiana Vasilcanu, Mårten Fryknäs, Luqman Sulaiman, Mohsen Karimi, Wen-Hui Weng, Weng-Onn Lui, Christina Rudduck, Magnus Axelson, Helena Jernberg-Wiklund, Leonard Girnita, Olle Larsson, Catharina Larsson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3056661?pdf=render

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http://europepmc.org/articles/PMC3056661?pdf=render

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