Mutation C3256T of mitochondrial genome in white blood cells: novel genetic marker of atherosclerosis and coronary heart disease.

This study was undertaken to examine the association between the level of heteroplasmy for the mutation C3256T in human white blood cells and the extent of carotid atherosclerosis, as well as the presence of coronary heart disease (CHD), the major clinical manifestation of atherosclerosis. Totally,...

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Bibliographic Details
Main Authors: Igor A Sobenin, Margarita A Sazonova, Maria M Ivanova, Andrey V Zhelankin, Veronika A Myasoedova, Anton Y Postnov, Serik D Nurbaev, Yuri V Bobryshev, Alexander N Orekhov
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3462756?pdf=render