Pre-stress performance in an instrumental training predict post-stress behavioral alterations in chronically stressed rats

Pre-stress performance in an instrumental training predict post-stress behavioral alterations in chronically stressed rats

Stress is a major factor in the development of major depressive disorder (MDD), but few studies have assessed individual risk based on pre-stress traits. In this study, we employed appetitive instrumental lever pressing with a progressive ratio schedule to assess the individual pre-stress behavioral...

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Bibliographic Details
Main Authors: Yoshio eIguchi, Sakurako eKosugi, Ziqiao eLin, Hiromi eNishikawa, Yoshio eMinabe, Shigenobu eToda
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-05-01
Series:Frontiers in Behavioral Neuroscience
Subjects:
individual difference
Major Depressive Disorder
chronic unpredictable stress
pre-stress traits
appetitive instrumental learning
post-stress phenotypes
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnbeh.2015.00119/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fnbeh.2015.00119/full

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