Hepatitis B virus core promoter mutations G1613A and C1653T are significantly associated with hepatocellular carcinoma in genotype C HBV-infected patients

<p>Abstract</p> <p>Background</p> <p>Hepatitis B virus (HBV) is a major cause of hepatocarcinogenesis.</p> <p>To identify mutations relevant to hepatocellular carcinoma (HCC) development, we compared the full genome sequences of HBV from the sera of patients...

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Main Authors: Fujioka Shin-Ichi, Kobashi Haruhiko, Iwasaki Yoshiaki, Koike Kazuko, Shiraha Hidenori, Takaki Akinobu, Tatsukawa Masashi, Sakaguchi Kohsaku, Yamamoto Kazuhide
Format: Article
Language:English
Published: BMC 2011-10-01
Series:BMC Cancer
Online Access:http://www.biomedcentral.com/1471-2407/11/458