MAVS: A Two-Sided CARD Mediating Antiviral Innate Immune Signaling and Regulating Immune Homeostasis

MAVS: A Two-Sided CARD Mediating Antiviral Innate Immune Signaling and Regulating Immune Homeostasis

Mitochondrial antiviral signaling protein (MAVS) functions as a “switch” in the immune signal transduction against most RNA viruses. Upon viral infection, MAVS forms prion-like aggregates by receiving the cytosolic RNA sensor retinoic acid-inducible gene I-activated signaling and further activates/s...

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Bibliographic Details
Main Authors:	Yunqiang Chen, Yuheng Shi, Jing Wu, Nan Qi
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2021-09-01
Series:	Frontiers in Microbiology
Subjects:	antiviral signal transduction immune homeostasis mitochondrial antiviral signaling protein post-translational modification viral evasion
Online Access:	https://www.frontiersin.org/articles/10.3389/fmicb.2021.744348/full

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