Species-specific vulnerability of RanBP2 shaped the evolution of SIV as it transmitted in African apes.
HIV-1 arose as the result of spillover of simian immunodeficiency viruses (SIVs) from great apes in Africa, namely from chimpanzees and gorillas. Chimpanzees and gorillas were, themselves, infected with SIV after virus spillover from African monkeys. During spillover events, SIV is thought to requir...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2018-03-01
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Series: | PLoS Pathogens |
Online Access: | http://europepmc.org/articles/PMC5843284?pdf=render |