2,3-Bifunctionalized Quinoxalines: Synthesis, DNA Interactions and Evaluation of Anticancer, Anti-tuberculosis and Antifungal Activity

2,3-Bifunctionalized Quinoxalines: Synthesis, DNA Interactions and Evaluation of Anticancer, Anti-tuberculosis and Antifungal Activity

A variety of 2,3-bifunctionalized quinoxalines (6-14) have been prepared by the condensation of 1,6-disubstituted-hexan-1,3,4,6-tetraones (1-4) with o-phenylenediamine, (R,R)-1,2-diaminocyclohexane and p-nitro-o-phenylenediamine. It is concluded that strong intramolecular N-H----O bonds in the favou...

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Bibliographic Details
Main Authors: Tom Ellis, Mohamed Bouakka, Abdelkader Hakkou, Sghir Elkadiri, Rachid Touzani, Abdelkrim Ramdani, Ann T. Kotchevar, Taibi Ben-Hadda, Michael J. Waring
Format: Article
Language:English
Published: MDPI AG 2002-08-01
Series:Molecules
Subjects:
Dissymmetric quinoxalines
DNA intercalator
Bayoud
Tuberculosis
Cancer
Online Access:http://www.mdpi.com/1420-3049/7/8/641/

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http://www.mdpi.com/1420-3049/7/8/641/

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