Molecular modelling and dynamic simulation of UDP-N-acetylglucosamine 1-carboxyvinyltransferase (MurA) from Mycobacterium tuberculosis using in silico approach
UDP-N-acetylglucosamine 1-carboxyvinyltransferase (MurA) catalyses the biosynthesis of peptidoglycans in Mycobacterium tuberculosis (MTB) cell wall by adding enolpyruvyl to UDP-N-acetylglucosamine through an addition and elimination process. In this study, novel inhibitors of MurA were identified us...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2018-01-01
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| Series: | Informatics in Medicine Unlocked |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2352914818301060 |