Elevated VEGF-D Modulates Tumor Inflammation and Reduces the Growth of Carcinogen-Induced Skin Tumors

Vascular endothelial growth factor D (VEGF-D) promotes the lymph node metastasis of cancer by inducing the growth of lymphatic vasculature, but its specific roles in tumorigenesis have not been elucidated. We monitored the effects of VEGF-D in cutaneous squamous cell carcinoma (cSCC) by subjecting t...

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Bibliographic Details
Main Authors: Hanne-Kaisa Honkanen, Valerio Izzi, Tiina Petäistö, Tanja Holopainen, Vanessa Harjunen, Taina Pihlajaniemi, Kari Alitalo, Ritva Heljasvaara
Format: Article
Language:English
Published: Elsevier 2016-07-01
Series:Neoplasia: An International Journal for Oncology Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558616300483