Structural Evidence for the Tetrameric Assembly of Chemokine CCL11 and the Glycosaminoglycan Arixtra™

Understanding chemokine interactions with glycosaminoglycans (GAG) is critical as these interactions have been linked to a number of inflammatory medical conditions, such as arthritis and asthma. To better characterize in vivo protein function, comprehensive knowledge of multimeric species, formed b...

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Bibliographic Details
Main Authors: Julie A. Leary, Andrew B. Dykstra, Matt D. Sweeney
Format: Article
Language:English
Published: MDPI AG 2013-11-01
Series:Biomolecules
Subjects:
Online Access:http://www.mdpi.com/2218-273X/3/4/905